1) The main ingredient of gelatin capsules with different raw materials is medicinal gelatin, which is derived from collagen in animal skin, tendons, and bones. The main ingredient of HPMC capsules is 2-Hydroxypropyl Methylcellulose, which is usually made by etherification of cellulose obtained by hydrolysis of plants.
2) The chemical structure and stability of the capsule shell are different. The residual lysine in the gelatin may cause a cross-linking reaction, while HPMC is chemically stable and will not undergo cross-linking reaction.
3) The water content of gelatin capsules with different water content is about 12.5-17.5%, the water content of hypromellose hollow capsules is about 4%-6%, and the water content of gelatin capsules below 10% will become brittle, while HPMC Even if the water content of the capsule reaches 1%, it will not become brittle, and it is more suitable for filling water-sensitive contents.
4) Different coating properties The surface of HPMC capsules is rougher than hollow capsules, and the affinity with most enteric coating materials is significantly higher than that of gelatin. The good coating performance of HPMC gives it obvious advantages in the preparation of sustained and controlled release coated capsules and targeted formulations.
5) The main component of gelatin capsules with different additives is protein, which is easy to breed bacteria, bacteria, and microorganisms. Preservatives and bacteriostatic agents need to be added during the production process, which may leave residues on the capsules, and the ring needs to be selected before packaging the finished product. Oxyethane is used to sterilize bacteria to ensure the microbial control indicators of the capsule. The HPMC capsule does not need to add any preservatives during the production process and does not need ethylene oxide to sterilize.
6) Different storage conditions. Tests have proved that HPMC capsules hardly become brittle under low-humidity conditions, and remain stable under high-humidity conditions. There is no problem in storage in all climatic zones.
Plant capsules are hollow glue made from plant cellulose materials. Plant capsules retain the advantages of traditional gelatin capsules: convenient to take, effective in masking taste and smell, and the contents are transparent and visible.
Moreover, compared with gelatin capsules, vegetable capsules have a tighter molecular structure, strong airtightness, and are not easily breathable, which effectively avoids the oxidation reaction of the medicine in contact with the air; it is not easy to breed bacteria, and it is not necessary to add carcinogens such as ethylene oxide or Irradiation for sterilization.
The plant capsules all use plant ingredients, which are harmless to the body. At the same time, they contain nutrients and are also effective for diabetes and high blood pressure. It is harmless to the body and contains nutrients. It is also effective for diabetes and high blood pressure.
