Zhejiang Tianlong Capsule Co., Ltd. was founded in 1987 and is a professional manufacturer of hollow capsules. At present, the company has two capsule production plants and 46 hollow capsule production lines installed. The plant area is strictly planned and designed according to the GMP standard for pharmaceutical excipients. The layout is scientific and reasonable. It has passed ISO9001 quality management system certification and is registered with the FDA in the United States. The company mainly produces 00#, 00#B, 0#el, 0#, 1#, 2#, 3#, 4# and other specifications of gelatin hollow capsules and plant capsules. At the same time can provide hundreds of colors for customers to choose, but also in accordance with the customer's color card number and sample custom production, the current annual production capacity has reached 26 billion.
Why Choose Us
Raw materials
We offer a vertically integrated supply chain model to ensure reliable long-term supply, complete traceability, and superior quality of raw materials. Our raw materials pass through strict quality control assessments before going to the manufacturing stage.
Complete qualifications
Our plant area is strictly planned and designed according to the GMP standard for pharmaceutical excipients. We have passed ISO9001, USFDA, HALAL quality management system certification and is registered with the FDA in the United States.
OEM & ODM service
We can provide hundreds of colors for customers to choose, but also in accordance with the customer's color card number and sample custom production.
Quality guaranteed
Advanced automated equipment and facilities, strict indoor cleanliness procedures and perfect quality real-time monitoring, as well as high-quality.
Low water content, suitable for water sensitive components. No risk of cross-linking reaction. The structure of elastic polymer ensures the stability of the capsule and the high filling rate.
Zhejiang Tianlong Capsule Co., Ltd. was founded in 1987 and is a professional manufacturer of hollow capsules. At present, the company has two capsule production plants and 46 hollow capsule production lines installed.
Our high quality, high performance HPMC(hydroxypropyl-methyl-cellulose) capsules meet a wide range of lifestyle, cultural and dietary needs, and are also well suited to moisture-sensitive formulations.
Hydroxypropyl Methylcellulose Capsule
Custom pharmaceutical grade drug in Halal natural plants cellulose print colored empty hard vegetable HPMC capsules
Halal food refers to food that meets Islamic Halal food standards. Islamic eating habits come from the canon. According to the canon, halal foods do not contain contraindications such as dead objects, blood and pork.
Our high quality, high performance HPMC (hydroxypropyl-methyl-cellulose) capsules meet a wide range of lifestyle, cultural and dietary needs, and are also well suited to moisture-sensitive formulations.
Custom pharmaceutical grade drug in Halal natural plants cellulose print colored empty hard vegetable HPMC capsules
Function/ The stomach dissolves, disintegrates, dissolves and absorbs rapidly in the stomach.
Capacity: Our annual output exceeds 26 billion capsules, which can meet the needs of customers with different purchase quantities.
What Is Vegan Gelatin Capsule
Vegan Gelatin Capsule have been used for almost 200 years in the pharmaceutical industry. They are an easy and effective delivery system for holding active pharmaceutical fills intended for oral use. Capsules provide an alternative to tablets, granules, and powders as oral dosage forms. They help increase the acceptance and ease of use of medications and work with a wide range of pharmaceutical ingredients, including liquids and solids. Gelatin is a pure, non-reactive, safe, and non-GMO material that allows for diverse applications. Gelatin capsules have dominated the empty capsules market, holding 88.5% of the $2.8 Bn global market share in 2021.
Benefits of Vegan Gelatin Capsule
Enhanced Bioavailability
These are known for their excellent bioavailability. Semi-solid and liquid content inside the capsules is easily absorbed by the body. Also, they deliver drugs faster and more efficiently. This feature is highly beneficial for drugs, especially for that who have low solubility or poor absorption in the gastrointestinal tract.
Accurate Dosage
This type of dosage form provides the precise and consistent dosing of active ingredients. The process of manufacturing ensures uniform distribution of the fill material, lowering the risk of dose variation between capsules. Also, precise dosing is very important for medications.
Easy Swallowing
As compared to traditional tablets or hard shell capsules, soft gelatin capsules are very easy to swallow. The smooth gel-like texture makes them less likely to stick in the throat and makes them the most comfortable option, especially for elderly patients and children as well.
Making Unpleasant Odors and Tastes
The shell of gelatin actually masks the taste and odor of the contents inside the capsule. Also, this is particularly supportive for drugs and supplements with unpleasant tastes or smells and making the patients more palatable.
Versatility
Soft Gelatin Capsules are filled with various types of materials such as oils, suspensions, and solid particles. This is very versatile and versatile making it more suitable for different types of medications and supplements.
Stability and Shelf Life
These offer superior protection to the contents from exposure to air, light, and moisture and improve stability that assists to extend the product shelf life. Also, it maintains the potency of the active ingredient over time.
Types of Vegan Gelatin Capsule
Hard capsules
These got their name from their stiff appearance when filled. They are a two-piece capsule system consisting of separable cylindrical gelatin shells– a shorter cap and a longer body, each closed at one end. The capsule has a slightly wider diameter, allowing the body to fit into it, forming a tight seal. Hard capsules are usually prefabricated and can be used to formulate solid, semisolid, and liquid pharmaceuticals.
Softgels
Are often one-piece hermetically sealed gelatin capsules used exclusively for formulating liquid and semisolid actives. There are various sizes, designs, and shapes of softgels that may be used for any of the above-listed reasons. In addition, twist-off and suckable softgels are made to give direct access to their content, as found in some vitamin products.
Medication Delivery
One of the primary applications of Vegan Gelatin Capsule is in the pharmaceutical industry. They are used to encapsulate various medications, ensuring that they are protected from environmental factors such as moisture and light. This protection is crucial for maintaining the potency and effectiveness of the medication.
Controlled Release
Vegan Gelatin Capsule can be engineered to have specific release properties, allowing for controlled release of the medication. This is particularly useful for drugs that need to be released gradually over time, such as pain relievers or anti-inflammatory medications.
Taste Masking
Many medications have a bitter or unpleasant taste. Vegan Gelatin Capsule can be used to mask these tastes, making the medication more palatable and improving patient compliance.
Stability and Shelf Life
The protective barrier provided by Vegan Gelatin Capsule helps in maintaining the stability of the medication, extending its shelf life. This is especially important for medications that are sensitive to environmental conditions.
How to Choose Vegan Gelatin Capsule
Active Pharmaceutical Ingredient (API) / Dissolution
This is the rate at which the capsule dissolves in the stomach allowing the active ingredient to be absorbed by the body. Gelatin, for example, has one of the best - if not the best - API dissolution rates, enabling the API to be quickly available for absorption by the body. It's one of the most important considerations for pharmaceutical manufacturers.
Cost-efficiency
Compared to alternative excipients, gelatin is the most cost-efficient. The ingredients for first generation HPMC hard capsules cost around four times more than gelatin and HPMC capsules cost around three times more to manufacture. This of course has an impact on the costs charged to the healthcare systems, the consumers and the taxpayers.
Machinability
Gelatin has a high level of machinability, which means it can tolerate the mechanical process really well, and therefore no additional ingredients or machines are needed. HPMC has a lower level of machinability: first generation HPMC requires secondary gelling agents, while second generation HPMC doesn't need gelling agents but does require machine adaptation.
Mechanical resistance
Capsules have to be strong enough to cope with mechanical stress. Any weakness can lead to defects. When compared to HPMC, gelatin is by far the most resistant. When it comes to soft capsules, gelatin and modified starch are of equal strength.
Oxygen permeability
Some APIs have complex profiles making them sensitive to oxidation. For these formulations, capsules are the best option as they offer the best protection. Because it has low oxygen permeability, gelatin is the best excipient when dealing with oxygen sensitive APIs. The alternative, HPMC, has a high potential for oxygen penetration which means other ingredients (such as antioxidants) have to be used, which increases the overall costs. So, wherever possible, manufacturers will always opt for gelatin capsules when oxygen sensitivity is a consideration.
Water permeability
Another consideration is moisture penetration. Vapor can have different impacts depending on the capsule type. HPMC has a lower water content than gelatin. However it's inconclusive as to whether HPMC actually performs better than gelatin in the area of water permeability.
Process of Vegan Gelatin Capsule
Formulation
The first step in manufacturing supplements is developing a specific formulation. This involves selecting the active ingredients for the product, such as vitamins, minerals, herbs, amino acids, or other ingredients. Each formulation is designed to provide specific health benefits. These ingredients must be carefully chosen for their efficacy, bioavailability, and safety.
Raw Material Procurement
Once the formulation is ready, manufacturers source high-quality raw materials from trusted suppliers. It's crucial to ensure that these raw materials are pure, safe, and meet all quality standards.
Raw Material Testing
The received raw materials are then tested for quality and purity. They are checked for contaminants and to verify that they meet the specified standards.
Mixing
The raw materials are then mixed together in specific doses according to the formula. This process ensures that each capsule contains the right amount of each ingredient.
Encapsulation
The mixed supplement is then filled into gelatin capsules. These capsules are made from gelatin derived from collagen, a protein found in animal tissues. Gelatin capsules are popular because they're easy to swallow, break down quickly in the stomach, and are cost-effective. The capsule can be filled with either powder, liquid, or even tiny beads or tablets (in the case of multi-particulate or multi-layer capsules).
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